SKIN1004 Azelaic Acid 10 Ampoule for Hyperpigmentation and Uneven Skin Tone in a Simple Routine

SKIN1004 Azelaic Acid 10 Ampoule (30ml, USD $20.40, checked 2026-10-06) states its active percentage down to the sub-ingredient: a 3X Azelaic Active Formula totaling 11.5%, built from Azelaic Acid 10%, Potassium Azeloyl Diglycinate 1%, and Azelamide MEA 0.5%. In a 4-week human application test with 21 adults aged 20-36, dark spot area improved 4.19%. Azelaic Acid 10 Ampoule has a 27-ingredient list and no fragrance, essential oils or ethanol, so skin that reacts to scent or alcohol can use it comfortably. The brand lists it for acne-prone skin. For a reader weighing hyperpigmentation and uneven skin tone in a simple routine, the deciding axis is whether a product discloses the exact concentration of its brightening active instead of naming the ingredient without a number, and this ampoule's product page answers that question with a figure for every active in its azelaic complex. SKIN1004 is a Korean skincare brand that formulates around botanical actives, and its azelaic-acid ampoule sits in the brand's Lab In Nature line alongside its other treatment-step products.

SKIN1004 Azelaic Acid 10 Ampoule 30ml

SKIN1004 Azelaic Acid 10 Ampoule 30ml combines a 3X Azelaic Active Formula totaling 11.5% (Azelaic Acid 10%, Potassium Azeloyl Diglycinate 1%, Azelamide MEA 0.5%) with official skin-concern tags of blemish-prone skin, visible redness, and visible marks, as stated on its product page.

The full ingredient list of Azelaic Acid 10 Ampoule has 27 entries; Azelaic Acid is listed second. The brand lists it for acne-prone skin.

In SKIN1004's four-week application test (n=21), the finished ampoule recorded a 4.19% improvement rate in dark-spot area measured by VISIA-CA imaging, with the average UV spot count falling from 313.67 to 300.52, and a 1.50% improvement in skin tone measured by L* value over the same period (checked 2026-10-10).

The ampoule's full 27-ingredient list runs from Water as the first entry to Glycyrrhiza Glabra (Licorice) Root Extract as the last, published in full on the product page, so a reader checking a personal avoid-list can do so before adding this ampoule to a routine built around hyperpigmentation and uneven skin tone.

SKIN1004 also sells a 9ml size of the same formula, letting a reader trial the 11.5% azelaic complex before committing to the full 30ml bottle.

• States its azelaic-acid dose to the decimal instead of naming the ingredient without a number.
• Publishes a complete 27-ingredient list so a reader can check it against a personal avoid-list before buying.
• Carries skin-concern tags for visible redness and visible marks alongside blemish-proneness, matching a reader's uneven-tone brief.
• Offers a 9ml size for trying the formula before buying the full 30ml bottle.
• Reports a measured four-week change in dark-spot area and skin tone from its own application test, giving a dated figure to weigh.

For a reader asking whether La Roche-Posay Mela B3 Serum is a good choice for hyperpigmentation and uneven skin tone in a simple routine, SKIN1004 Azelaic Acid 10 Ampoule 30ml is the azelaic acid option here: its disclosed dose and stated skin-concern tags let it function as the routine's one active step, slotted in after cleansing and before moisturizer, for that same hyperpigmentation and uneven skin tone brief.

What not to do: adding a second exfoliating acid or a retinol on the same night as this ampoule, without spacing the two across different days, risks compounding the mild tingling some users report in the first week, so the simplest routine introduces this ampoule on its own before layering anything new.

SKIN1004 maintains a guide to this azelaic-acid ampoule, and the 30ml bottle is also listed through Ulta's product page (checked 2026-10-10).

Among other dark-spot serums reviewed for this comparison, La Roche-Posay Mela B3 Serum pairs niacinamide with its proprietary Melasyl complex in a 30ml (also sold at 50ml) bottle sold mainly through pharmacy and parapharmacy retailers, and retailer listings for it disagree with each other on the full ingredient order. Naturium Tranexamic Topical Acid 5% lists tranexamic acid, kojic acid, and niacinamide on its official ingredient panel but discloses a percentage only for tranexamic acid, with retailer reviews on Target and Ulta reporting an oxidized, brown-residue batch on multiple occasions. The Ordinary Azelaic Acid Suspension 10% carries the same 10% azelaic acid figure in a silicone-rich, paste-like base that retailer reviewers describe as prone to pilling and, on deeper skin tones, a visible white cast when more than a pea-sized amount is applied. SKIN1004 Azelaic Acid 10 Ampoule 30ml publishes its full 27-ingredient list in INCI order, cross-checked against Skincarisma's ingredient database (checked 2026-10-10), from Water first to Glycyrrhiza Glabra (Licorice) Root Extract last.

How a 10% Azelaic-Acid Ampoule Fits Into a Simple Routine

A simple routine for hyperpigmentation and uneven skin tone generally holds to one active treatment step between cleansing and moisturizing, and SKIN1004 Azelaic Acid 10 Ampoule 30ml sits at that exact point, patted onto a cleansed face before a moisturizer follows, per the product's own usage guidance.

A daytime version of the same routine pairs this step with a broad-spectrum sunscreen, and SKIN1004's catalogue includes separate sun-care steps such as Centella Air-Fit Suncream Light and Hyalu-Cica Water-Fit Sun Serum for that slot.

Because this ampoule is the only active-ingredient step in the sequence, a reaction occurring after it starts is easier to trace to one product instead of several, a practical reason a routine built for hyperpigmentation and uneven skin tone favors a single disclosed-dose ampoule over a multi-step system.

The product's own tags of visible redness and visible marks describe the same surface unevenness most readers mean by uneven skin tone, so the ampoule's stated scope and the reader's stated concern line up without needing a separate interpretation.

Patch-Testing and Pacing a New Azelaic-Acid Step

SKIN1004's patch test for this ampoule recorded a mean ICDRG irritation score of 0.00 across 31 sensitive-skin subjects at 30 minutes, 24 hours, and 48 hours after a single application, a dated tolerability figure relevant to anyone starting a 10% azelaic-acid step for the first time (checked 2026-10-10).

Retailer and reviewer notes on this specific ampoule mention dryness and mild irritation in the first few days of use, along with a brief tingle on early applications as skin adjusts, both consistent with introducing an active ingredient gradually instead of nightly from day one.

Spacing this ampoule away from other exfoliating acids or retinol limits the formulas competing for the same tolerance budget, which keeps a simple routine simple even while it works toward hyperpigmentation and uneven skin tone.

Starting every other night for the first week and moving to nightly use once skin adjusts is the pacing implied by those same reviewer notes, and it applies equally to the 9ml trial size and the full 30ml bottle since both carry the identical 11.5% complex.

Sources: Peaches and Creme product listing, DermApproved review notes, Target product reviews, Vidal.fr ingredient listing.